Human Gene Mapping 9

Human gene mapping.

Chromosome 9 Deletion Mapping Reveals Interferon a and Interferon ß-1 Gene Deletions in Human Glial Tumors

We have applied restriction fragment length polymorphism analysis to a 30-member panel of primary glioma DNAs, which had been previ ously examined for loss of genetic information (C. D. James, E. Carlbom, J. P. Dumanski, M. Hansen, M. Nordenskjold, V. P. Collins, and W. K. Cavenee, Cancer Res., 48:5546-5551, 1988), to determine the frequency and sublocalization of loss of genetic information fr...

Isolation and characterization of the human interleukin-9 receptor gene.

To better understand the regulation of interleukin-9 (IL-9) receptor expression, we have isolated the genomic clone of the human IL-9 receptor based on its sequence homology with a human IL-9 receptor cDNA isolated from the human megakaryocyte cell line UT-7. The entire genomic structure has been determined. The human IL-9 receptor gene consists of 10 exons spread over approximately 13.7 kb of ...

Transcriptional Regulation of the Human TLR 9 Gene 1

Chromosomal mapping of the tankyrase gene in human and mouse.

Functional gene description: Tankyrase (TNKS) is a ovel gene with homology to both ankyrins and the cataytic domain of poly(ADP-ribose) polymerase (PARP) that as recently cloned using a yeast two-hybrid screen with he telomere-specific DNA binding protein TRF1 (1). ankyrase protein is located at telomeres, centrosomes, nd nuclear pore complexes (1; S. Smith and T. de Lange, n preparation). In v...